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Continuous Light Does Not Affect Atherosclerosis in APOE*3-Leiden.CETP Mice. J Biol Rhythms. 2020;35(6):598-611.
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Inhibition of Cholesteryl Ester Transfer Protein Preserves High-Density Lipoprotein Cholesterol and Improves Survival in Sepsis. Circulation. 2020.
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Deficiency of the Circadian Clock Gene Bmal1 Reduces Microglial Immunometabolism. Front Immunol. 2020;11:586399.
Yoneshiro T, Rodriguez-Rodriguez R, Betz MJ, Rensen PCN. Editorial: Current Challenges for Targeting Brown Fat Thermogenesis to Combat Obesity. Front Endocrinol (Lausanne). 2020;11:600341.
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Colesevelam enhances the beneficial effects of brown fat activation on hyperlipidaemia and atherosclerosis development. Cardiovasc Res. 2020;116(10):1710-20.
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Human Brown Adipose Tissue Estimated With Magnetic Resonance Imaging Undergoes Changes in Composition After Cold Exposure: An in vivo MRI Study in Healthy Volunteers. Front Endocrinol (Lausanne). 2019;10:898.
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Proteoglycan 4 deficiency protects against glucose intolerance and fatty liver disease in diet-induced obese mice. Biochim Biophys Acta Mol Basis Dis. 2019;1865(2):494-501.
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Vrieling F, Wilson L, Rensen PCN, Walzl G, Ottenhoff THM, Joosten SA. Oxidized low-density lipoprotein (oxLDL) supports Mycobacterium tuberculosis survival in macrophages by inducing lysosomal dysfunction. PLoS Pathog. 2019;15(4):e1007724.
Worthmann A, Schlein C, Berbée JFP, Rensen PCN, Heeren J, Bartelt A. Effects of Pharmacological Thermogenic Adipocyte Activation on Metabolism and Atherosclerotic Plaque Regression. Nutrients. 2019;11(2).
Bijkerk R, Trimpert C, van Solingen C, de Bruin RG, Florijn BW, Kooijman S, et al. MicroRNA-132 controls water homeostasis through regulating MECP2-mediated vasopressin synthesis. Am J Physiol Renal Physiol. 2018;315(4):F1129-f38.
Blauw LL, Li Z, Rensen SS, Greve JWM, Verhoeven A, Derks RJ, et al. Metabolic liver inflammation in obesity does not robustly decrease hepatic and circulating CETP. Atherosclerosis. 2018;275:149-55.
Blauw LL, Li-Gao R, Noordam R, de Mutsert R, Trompet S, Berbée JFP, et al. CETP (Cholesteryl Ester Transfer Protein) Concentration: A Genome-Wide Association Study Followed by Mendelian Randomization on Coronary Artery Disease. Circ Genom Precis Med. 2018;11(5):e002034.
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Dekker SA, Noordam R, Biermasz NR, de Roos A, Lamb HJ, Rosendaal FR, et al. Habitual Sleep Measures are Associated with Overall Body Fat, and not Specifically with Visceral Fat, in Men and Women. Obesity (Silver Spring). 2018;26(10):1651-8.
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Kuipers EN, Dam ADV, Held NM, Mol IM, Houtkooper RH, Rensen PCN, et al. Quercetin Lowers Plasma Triglycerides Accompanied by White Adipose Tissue Browning in Diet-Induced Obese Mice. Int J Mol Sci. 2018;19(6).
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Kuipers EN, van Dam AD, Ballak DB, de Wit EA, Dinarello CA, Stienstra R, et al. IL-37 Expression Reduces Lean Body Mass in Mice by Reducing Food Intake. Int J Mol Sci. 2018;19(8).
Li Z, Yi CX, Katiraei S, Kooijman S, Zhou E, Chung CK, et al. Butyrate reduces appetite and activates brown adipose tissue via the gut-brain neural circuit. Gut. 2018;67(7):1269-79.
Li-Gao R, de Mutsert R, Rensen PCN, van Klinken JB, Prehn C, Adamski J, et al. Postprandial metabolite profiles associated with type 2 diabetes clearly stratify individuals with impaired fasting glucose. Metabolomics. 2018;14(1):13.
Martinez-Tellez B, Nahon KJ, Sanchez-Delgado G, Abreu-Vieira G, Llamas-Elvira JM, van Velden FHP, et al. The impact of using BARCIST 1.0 criteria on quantification of BAT volume and activity in three independent cohorts of adults. Sci Rep. 2018;8(1):8567.
Martinez-Tellez B, Xu H, Sanchez-Delgado G, Acosta FM, Rensen PCN, Llamas-Elvira JM, et al. Association of wrist and ambient temperature with cold-induced brown adipose tissue and skeletal muscle [(18)F]FDG uptake in young adults. Am J Physiol Regul Integr Comp Physiol. 2018;315(6):R1281-r8.
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Ruiz JR, Martinez-Tellez B, Sanchez-Delgado G, Osuna-Prieto FJ, Rensen PCN, Boon MR. Role of Human Brown Fat in Obesity, Metabolism and Cardiovascular Disease: Strategies to Turn Up the Heat. Prog Cardiovasc Dis. 2018;61(2):232-45.
Schilperoort M, van Dam AD, Hoeke G, Shabalina IG, Okolo A, Hanyaloglu AC, et al. The GPR120 agonist TUG-891 promotes metabolic health by stimulating mitochondrial respiration in brown fat. EMBO Mol Med. 2018;10(3).
Spaanderman DCE, Nixon M, Buurstede JC, Sips HC, Schilperoort M, Kuipers EN, et al. Androgens modulate glucocorticoid receptor activity in adipose tissue and liver. J Endocrinol. 2018.
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van Dam AD, van Beek L, Pronk ACM, van den Berg SM, Van den Bossche J, de Winther MPJ, et al. IgG is elevated in obese white adipose tissue but does not induce glucose intolerance via Fcγ-receptor or complement. Int J Obes (Lond). 2018;42(2):260-9.
van den Berg R, Kooijman S, Noordam R, Ramkisoensing A, Abreu-Vieira G, Tambyrajah LL, et al. A Diurnal Rhythm in Brown Adipose Tissue Causes Rapid Clearance and Combustion of Plasma Lipids at Wakening. Cell Rep. 2018;22(13):3521-33.
van der Tuin SJL, Li Z, Berbée JFP, Verkouter I, Ringnalda LE, Neele AE, et al. Lipopolysaccharide Lowers Cholesteryl Ester Transfer Protein by Activating F4/80(+)Clec4f(+)Vsig4(+)Ly6C(-) Kupffer Cell Subsets. J Am Heart Assoc. 2018;7(6).
van Eenige R, van der Stelt M, Rensen PCN, Kooijman S. Regulation of Adipose Tissue Metabolism by the Endocannabinoid System. Trends Endocrinol Metab. 2018;29(5):326-37.
van Eyk HJ, van Schinkel LD, Kantae V, Dronkers CEA, Westenberg JJM, de Roos A, et al. Caloric restriction lowers endocannabinoid tonus and improves cardiac function in type 2 diabetes. Nutr Diabetes. 2018;8(1):6.
van Loon NM, Ottenhoff R, Kooijman S, Moeton M, Scheij S, Roscam Abbing RLP, et al. Inactivation of the E3 Ubiquitin Ligase IDOL Attenuates Diet-Induced Obesity and Metabolic Dysfunction in Mice. Arterioscler Thromb Vasc Biol. 2018;38(8):1785-95.
van Loon NM, Rensen PCN, Zelcer N. IDOL in metabolic, neurodegenerative and cardiovascular disease. Aging (Albany NY). 2018;10(11):3042-3.
Bartelt A, John C, Schaltenberg N, Berbée JFP, Worthmann A, Cherradi ML, et al. Thermogenic adipocytes promote HDL turnover and reverse cholesterol transport. Nat Commun. 2017;8:15010.
Berbée JFP, Mol IM, Milne GL, Pollock E, Hoeke G, Lütjohann D, et al. Deuterium-reinforced polyunsaturated fatty acids protect against atherosclerosis by lowering lipid peroxidation and hypercholesterolemia. Atherosclerosis. 2017;264:100-7.
Blauw LL, Aziz NA, Tannemaat MR, Blauw CA, de Craen AJ, Pijl H, et al. Diabetes incidence and glucose intolerance prevalence increase with higher outdoor temperature. BMJ Open Diabetes Res Care. 2017;5(1):e000317.
Blauw LL, Noordam R, Trompet S, Berbée JFP, Rosendaal FR, van Heemst D, et al. Genetic variation in the obesity gene FTO is not associated with decreased fat oxidation: the NEO study. Int J Obes (Lond). 2017;41(10):1594-600.
Boon MR, Bakker LEH, Prehn C, Adamski J, Vosselman MJ, Jazet IM, et al. LysoPC-acyl C16:0 is associated with brown adipose tissue activity in men. Metabolomics. 2017;13(5):48.
Bus P, Pierneef L, Bor R, Wolterbeek R, van Es LA, Rensen PC, et al. Apolipoprotein C-I plays a role in the pathogenesis of glomerulosclerosis. J Pathol. 2017;241(5):589-99.
Christen T, de Mutsert R, Gast KB, Rensen PCN, de Koning E, Rosendaal FR, et al. Association of fasting triglyceride concentration and postprandial triglyceride response with the carotid intima-media thickness in the middle aged: The Netherlands Epidemiology of Obesity study. J Clin Lipidol. 2017;11(2):377-85.e1.
Deng H, Kooijman S, van den Nieuwendijk AM, Ogasawara D, van der Wel T, van Dalen F, et al. Triazole Ureas Act as Diacylglycerol Lipase Inhibitors and Prevent Fasting-Induced Refeeding. J Med Chem. 2017;60(1):428-40.
Hoeke G, Khedoe P, van Diepen JA, Pike-Overzet K, van de Ven B, Vazirpanah N, et al. The Effects of Selective Hematopoietic Expression of Human IL-37 on Systemic Inflammation and Atherosclerosis in LDLr-Deficient Mice. Int J Mol Sci. 2017;18(8).
Hoeke G, Nahon KJ, Bakker LEH, Norkauer SSC, Dinnes DLM, Kockx M, et al. Short-term cooling increases serum triglycerides and small high-density lipoprotein levels in humans. J Clin Lipidol. 2017;11(4):920-8.e2.
Hoeke G, Wang Y, van Dam AD, Mol IM, Gart E, Klop HG, et al. Atorvastatin accelerates clearance of lipoprotein remnants generated by activated brown fat to further reduce hypercholesterolemia and atherosclerosis. Atherosclerosis. 2017;267:116-26.
Kantae V, Nahon KJ, Straat ME, Bakker LEH, Harms AC, van der Stelt M, et al. Endocannabinoid tone is higher in healthy lean South Asian than white Caucasian men. Sci Rep. 2017;7(1):7558.
Katiraei S, Hoving LR, van Beek L, Mohamedhoesein S, Carlotti F, van Diepen JA, et al. BMT decreases HFD-induced weight gain associated with decreased preadipocyte number and insulin secretion. PLoS One. 2017;12(4):e0175524.
Khedoe P, de Kleijn S, van Oeveren-Rietdijk AM, Plomp JJ, de Boer HC, van Pel M, et al. Acute and chronic effects of treatment with mesenchymal stromal cells on LPS-induced pulmonary inflammation, emphysema and atherosclerosis development. PLoS One. 2017;12(9):e0183741.
Martinez-Tellez B, Sanchez-Delgado G, Boon MR, Rensen PCN, Ruiz JR. Activation and quantification of human brown adipose tissue: Methodological considerations for between studies comparisons: Comment on: Hot heads & cool bodies: The conundrums of human BAT activity research. Eur J Intern Med. 2017;40:e19-e21.
Martinez-Tellez B, Sanchez-Delgado G, Garcia-Rivero Y, Alcantara JMA, Martinez-Avila WD, Muñoz-Hernandez MV, et al. A New Personalized Cooling Protocol to Activate Brown Adipose Tissue in Young Adults. Front Physiol. 2017;8:863.
Nahon KJ, Boon MR, Doornink F, Jazet IM, Rensen PCN, Abreu-Vieira G. Lower critical temperature and cold-induced thermogenesis of lean and overweight humans are inversely related to body mass and basal metabolic rate. J Therm Biol. 2017;69:238-48.
Paalvast Y, Gerding A, Wang Y, Bloks VW, van Dijk TH, Havinga R, et al. Male apoE*3-Leiden.CETP mice on high-fat high-cholesterol diet exhibit a biphasic dyslipidemic response, mimicking the changes in plasma lipids observed through life in men. Physiol Rep. 2017;5(19).
Paulin N, Döring Y, Kooijman S, Blanchet X, Viola JR, de Jong R, et al. Human Neutrophil Peptide 1 Limits Hypercholesterolemia-induced Atherosclerosis by Increasing Hepatic LDL Clearance. EBioMedicine. 2017;16:204-11.
van Dam AD, Boon MR, Berbée JFP, Rensen PCN, van Harmelen V. Targeting white, brown and perivascular adipose tissue in atherosclerosis development. Eur J Pharmacol. 2017;816:82-92.
van Dam AD, Hanssen MJW, van Eenige R, Quinten E, Sips HC, Hülsman CJM, et al. South Asian men have lower expression of IFN signalling genes in white adipose tissue and skeletal muscle compared with white men. Diabetologia. 2017;60(12):2525-8.
van den Berg R, Noordam R, Kooijman S, Jansen SWM, Akintola AA, Slagboom PE, et al. Familial longevity is characterized by high circadian rhythmicity of serum cholesterol in healthy elderly individuals. Aging Cell. 2017;16(2):237-43.
van den Berg SM, van Dam AD, Kusters PJH, Beckers L, den Toom M, van der Velden S, et al. Helminth antigens counteract a rapid high-fat diet-induced decrease in adipose tissue eosinophils. J Mol Endocrinol. 2017;59(3):245-55.
van den Berg SM, van Dam AD, Rensen PC, de Winther MP, Lutgens E. Immune Modulation of Brown(ing) Adipose Tissue in Obesity. Endocr Rev. 2017;38(1):46-68.
Bakker LE, Boon MR, Annema W, Dikkers A, van Eyk HJ, Verhoeven A, et al. HDL functionality in South Asians as compared to white Caucasians. Nutr Metab Cardiovasc Dis. 2016;26(8):697-705.
Blauw LL, de Mutsert R, Lamb HJ, de Roos A, Rosendaal FR, Jukema JW, et al. Serum CETP concentration is not associated with measures of body fat: The NEO study. Atherosclerosis. 2016;246:267-73.
Hoeke G, Kooijman S, Boon MR, Rensen PC, Berbée JF. Role of Brown Fat in Lipoprotein Metabolism and Atherosclerosis. Circ Res. 2016;118(1):173-82.
Khedoe PP, Rensen PC, Berbée JF, Hiemstra PS. Murine models of cardiovascular comorbidity in chronic obstructive pulmonary disease. Am J Physiol Lung Cell Mol Physiol. 2016;310(11):L1011-27.
Kockx M, Glaros E, Leung B, Ng TW, Berbée JF, Deswaerte V, et al. Low-Density Lipoprotein Receptor-Dependent and Low-Density Lipoprotein Receptor-Independent Mechanisms of Cyclosporin A-Induced Dyslipidemia. Arterioscler Thromb Vasc Biol. 2016;36(7):1338-49.
Laurila PP, Soronen J, Kooijman S, Forsström S, Boon MR, Surakka I, et al. USF1 deficiency activates brown adipose tissue and improves cardiometabolic health. Sci Transl Med. 2016;8(323):323ra13.
Louwe MC, Lammers B, Frias MA, Foks AC, de Leeuw LR, Hildebrand RB, et al. Abca1 deficiency protects the heart against myocardial infarction-induced injury. Atherosclerosis. 2016;251:159-63.
Marsch E, Demandt JA, Theelen TL, Tullemans BM, Wouters K, Boon MR, et al. Deficiency of the oxygen sensor prolyl hydroxylase 1 attenuates hypercholesterolaemia, atherosclerosis, and hyperglycaemia. Eur Heart J. 2016;37(39):2993-7.
Mook-Kanamori DO, de Mutsert R, Rensen PC, Prehn C, Adamski J, den Heijer M, et al. Type 2 diabetes is associated with postprandial amino acid measures. Arch Biochem Biophys. 2016;589:138-44.
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